Actin-related protein 3B (ACTR3B)
Homo sapiens — UniProt Q9P1U1
Data last refreshed: (UniProt release unknown)
Key facts
Actin-related protein 3B (ACTR3B) is a protein from Homo sapiens identified by UniProt accession Q9P1U1, 418 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9P1U1; gene symbol ACTR3B.
- Organism: Homo sapiens.
- Length: 418 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, PHF-tau measurement and Autosomal dominant striatal neurodegeneration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-related protein 3B |
|---|---|
| UniProt accession | Q9P1U1 |
| Gene | ACTR3B |
| Organism | Homo sapiens |
| Length | 418 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.19
- PHF-tau measurement · score 0.18
- Autosomal dominant striatal neurodegeneration · score 0.04
- shoulder fracture · score 0.04
- glioblastoma multiforme · score 0.01
- cancer · score 0.01
- psoriasis · score 0.01
- neoplasm · score 0.01
- Huntington disease · score 0.01
- colorectal adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P1U1-F1 | alphafold | PREDICTED | 93.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1U1.
Amino-acid sequence (418 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACTR3B?
The strongest Open Targets associations for ACTR3B are gut microbiome measurement, PHF-tau measurement, Autosomal dominant striatal neurodegeneration, shoulder fracture and glioblastoma multiforme.
How long is the ACTR3B protein?
The Homo sapiens ACTR3B protein (UniProt Q9P1U1) is 418 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P1U1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P1U1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.