Sterile alpha motif domain-containing protein 15 (SAMD15)
Homo sapiens — UniProt Q9P1V8
Data last refreshed: (UniProt release unknown)
Key facts
Sterile alpha motif domain-containing protein 15 (SAMD15) is a protein from Homo sapiens identified by UniProt accession Q9P1V8, 674 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q9P1V8; gene symbol SAMD15.
- Organism: Homo sapiens.
- Length: 674 amino acids.
- Top disease associations (Open Targets): neutrophil count, neurodegenerative disease and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sterile alpha motif domain-containing protein 15 |
|---|---|
| UniProt accession | Q9P1V8 |
| Gene | SAMD15 |
| Organism | Homo sapiens |
| Length | 674 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.37
- neurodegenerative disease · score 0.35
- leukocyte count · score 0.33
- myeloid white cell count · score 0.33
- granulocyte count · score 0.20
- eosinophil count · score 0.19
- sum of basophil and neutrophil counts · score 0.15
- sum of neutrophil and eosinophil counts · score 0.15
- apolipoprotein A 1 measurement · score 0.09
- neutrophil percentage of leukocytes · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P1V8-F1 | alphafold | PREDICTED | 49.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1V8.
Amino-acid sequence (674 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAMD15?
The strongest Open Targets associations for SAMD15 are neutrophil count, neurodegenerative disease, leukocyte count, myeloid white cell count and granulocyte count.
How long is the SAMD15 protein?
The Homo sapiens SAMD15 protein (UniProt Q9P1V8) is 674 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P1V8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P1V8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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