Zinc finger and BTB domain-containing protein 4 (ZBTB4)
Homo sapiens — UniProt Q9P1Z0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 4 (ZBTB4) is a protein from Homo sapiens identified by UniProt accession Q9P1Z0, 1013 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.
- UniProt accession: Q9P1Z0; gene symbol ZBTB4.
- Organism: Homo sapiens.
- Length: 1013 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hemoglobin measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 4 |
|---|---|
| UniProt accession | Q9P1Z0 |
| Gene | ZBTB4 |
| Organism | Homo sapiens |
| Length | 1013 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (106)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- hemoglobin measurement · score 0.23
- body height · score 0.22
- lean body mass · score 0.22
- sex hormone-binding globulin measurement · score 0.21
- heel bone mineral density · score 0.21
- leukocyte count · score 0.19
- appendicular lean mass · score 0.19
- BMI-adjusted waist circumference · score 0.18
- fat body mass · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P1Z0-F1 | alphafold | PREDICTED | 48.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P1Z0.
Amino-acid sequence (1013 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB4?
The strongest Open Targets associations for ZBTB4 are neurodegenerative disease, hemoglobin measurement, body height, lean body mass and sex hormone-binding globulin measurement.
How long is the ZBTB4 protein?
The Homo sapiens ZBTB4 protein (UniProt Q9P1Z0) is 1013 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P1Z0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P1Z0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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