About Calcium-binding and coiled-coil domain-containing protein 1
Calcium-binding and coiled-coil domain-containing protein 1 (CALCOCO1) is a protein
from Homo sapiens identified by UniProt accession
Q9P1Z2, 691 residues long.
MolForge cross-references it against 0 known binders and
62 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (62)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.19
- ulna fracture · score 0.08
- radius fracture · score 0.08
- retinitis pigmentosa · score 0.06
- Familial exudative vitreoretinopathy · score 0.05
- mean corpuscular hemoglobin concentration · score 0.05
- snowflake vitreoretinal degeneration · score 0.04
- hypoparathyroidism, familial isolated, 2 · score 0.04
- Bardet-Biedl syndrome · score 0.04
- Familial drusen · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q9P1Z2.
Amino-acid sequence (691 residues)
MEESPLSRAP SRGGVNFLNV ARTYIPNTKV ECHYTLPPGT MPSASDWIGI FKVEAACVRD YHTFVWSSVP ESTTDGSPIH TSVQFQASYL PKPGAQLYQF RYVNRQGQVC GQSPPFQFRE PRPMDELVTL EEADGGSDIL LVVPKATVLQ NQLDESQQER NDLMQLKLQL EGQVTELRSR VQELERALAT ARQEHTELME QYKGISRSHG EITEERDILS RQQGDHVARI LELEDDIQTI SEKVLTKEVE LDRLRDTVKA LTREQEKLLG QLKEVQADKE QSEAELQVAQ QENHHLNLDL KEAKSWQEEQ SAQAQRLKDK VAQMKDTLGQ AQQRVAELEP LKEQLRGAQE LAASSQQKAT LLGEELASAA AARDRTIAEL HRSRLEVAEV NGRLAELGLH LKEEKCQWSK ERAGLLQSVE AEKDKILKLS AEILRLEKAV QEERTQNQVF KTELAREKDS SLVQLSESKR ELTELRSALR VLQKEKEQLQ EEKQELLEYM RKLEARLEKV ADEKWNEDAT TEDEEAAVGL SCPAALTDSE DESPEDMRLP PYGLCERGDP GSSPAGPREA SPLVVISQPA PISPHLSGPA EDSSSDSEAE DEKSVLMAAV QSGGEEANLL LPELGSAFYD MASGFTVGTL SETSTGGPAT PTWKECPICK ERFPAESDKD ALEDHMDGHF FFSTQDPFTF E
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