RNA-binding protein 27 (RBM27)
Homo sapiens — UniProt Q9P2N5
Data last refreshed: (UniProt release unknown)
Key facts
RNA-binding protein 27 (RBM27) is a protein from Homo sapiens identified by UniProt accession Q9P2N5, 1060 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9P2N5; gene symbol RBM27.
- Organism: Homo sapiens.
- Length: 1060 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Red cell distribution width and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RNA-binding protein 27 |
|---|---|
| UniProt accession | Q9P2N5 |
| Gene | RBM27 |
| Organism | Homo sapiens |
| Length | 1060 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- Red cell distribution width · score 0.39
- neurofibrillary tangles measurement · score 0.10
- mathematical ability · score 0.05
- self reported educational attainment · score 0.04
- age at onset · score 0.04
- Alzheimer disease · score 0.04
- Autism · score 0.02
- Neurodevelopmental disorder · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P2N5-F1 | alphafold | PREDICTED | 54.90 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P2N5.
Amino-acid sequence (1060 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RBM27?
The strongest Open Targets associations for RBM27 are neurodegenerative disease, Red cell distribution width, neurofibrillary tangles measurement, mathematical ability and self reported educational attainment.
How long is the RBM27 protein?
The Homo sapiens RBM27 protein (UniProt Q9P2N5) is 1060 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P2N5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P2N5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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