Protein NYNRIN (NYNRIN)

Homo sapiens — UniProt Q9P2P1

Gene: NYNRINHomo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Protein NYNRIN (NYNRIN) is a protein from Homo sapiens identified by UniProt accession Q9P2P1, 1898 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.

UniProt accession: Q9P2P1; gene symbol NYNRIN.
Organism: Homo sapiens.
Length: 1898 amino acids.
Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, neurodegenerative disease and sex hormone-binding globulin measurement.
3D structure: AlphaFold model available.

Target properties

Protein name	Protein NYNRIN
UniProt accession	Q9P2P1
Gene	NYNRIN
Organism	Homo sapiens
Length	1898 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (55)

Diseases linked to this target (Open Targets).

low density lipoprotein cholesterol measurement · score 0.42
neurodegenerative disease · score 0.39
sex hormone-binding globulin measurement · score 0.38
total cholesterol measurement · score 0.38
alkaline phosphatase measurement · score 0.37
C-reactive protein measurement · score 0.37
serum alanine aminotransferase measurement · score 0.36
calcium measurement · score 0.35
hemoglobin measurement · score 0.35
testosterone measurement · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9P2P1-F1	alphafold	PREDICTED	59.04	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P2P1.

Amino-acid sequence (1898 residues)

MLLSGGDPPA QEWFMVQTKS KPRVQRQRLQ VQRIFRVKLN AFQSRPDTPY FWLQLEGPRE NMGKAKEYLK GLCSPELWKE VRYPPILHCA FLGAQGLFLD CLCWSTLAYL VPGPPGSLMV GGLTESFIMT QNWLEELVGR LRWGPAPLLT PRGIWEAEVT RAFGALVWIR GDQHAGDLLQ LPPAVQELLL SLVRDAAGKE DIIEWLSRFG ISDSHSDPEV LICPPQQQKE APAMVSVGES PGPFVDMGTL QNRGPENSKR LSSLGATGSL ITAQSTPQEA ANQLVRVGSN NQDGMDSAQE EGTVQATSSQ DSTNHTQALL KQRQVQKIED KLLFQPPVSA LGVCPPWKAW TPGPAFGPLW PGAIAATFWR INELHSLHLA WLLSQACFNF PFWQRPLGPI QLKLPGQNPL PLNLEWKQKE LAPLPSAESP AGRPDGGLGG EAALQNCPRP EISPKVTSLL VVPGSSDVKD KVSSDLPQIG PPLTSTPQLQ AGGEPGDQGS MQLDFKGLEE GPAPVLPTGQ GKPVAQGGLT DQSVPGAQTV PETLKVPMAA AVPKAENPSR TQVPSAAPKL PTSRMMLAVH TEPAAPEVPL APTKPTAQLM ATAQKTVVNQ PVLVAQVEPT TPKTPQAQKM PVAKTSPAGP KTPKAQAGPA ATVSKAPAAS KAPAAPKVPV TPRVSRAPKT PAAQKVPTDA GPTLDVARLL SEVQPTSRAS VSLLKGQGQA GRQGPQSSGT LALSSKHQFQ MEGLLGAWEG APRQPPRHLQ ANSTVTSFQR YHEALNTPFE LNLSGEPGNQ GLRRVVIDGS SVAMVHGLQH FFSCRGIAMA VQFFWNRGHR EVTVFVPTWQ LKKNRRVRES HFLTKLHSLK MLSITPSQLE NGKKITTYDY RFMVKLAEET DGIIVTNEQI HILMNSSKKL MVKDRLLPFT FAGNLFMVPD DPLGRDGPTL DEFLKKPNRL DTDIGNFLKV WKTLPPSSAS VTELSDDADS GPLESLPNME EVREEKEERQ DEEQRQGQGT QKAAEEDDLD SSLASVFRVE CPSLSEEILR CLSLHDPPDG ALDIDLLPGA ASPYLGIPWD GKAPCQQVLA HLAQLTIPSN FTALSFFMGF MDSHRDAIPD YEALVGPLHS LLKQKPDWQW DQEHEEAFLA LKRALVSALC LMAPNSQLPF RLEVTVSHVA LTAILHQEHS GRKHPIAYTS KPLLPDEESQ GPQSGGDSPY AVAWALKHFS RCIGDTPVVL DLSYASRTTA DPEVREGRRV SKAWLIRWSL LVQDKGKRAL ELALLQGLLG ENRLLTPAAS MPRFFQVLPP FSDLSTFVCI HMSGYCFYRE DEWCAGFGLY VLSPTSPPVS LSFSCSPYTP TYAHLAAVAC GLERFGQSPL PVVFLTHCNW IFSLLWELLP LWRARGFLSS DGAPLPHPSL LSYIISLTSG LSSLPFIYRT SYRGSLFAVT VDTLAKQGAQ GGGQWWSLPK DVPAPTVSPH AMGKRPNLLA LQLSDSTLAD IIARLQAGQK LSGSSPFSSA FNSLSLDKES GLLMFKGDKK PRVWVVPTQL RRDLIFSVHD IPLGAHQRPE ETYKKLRLLG WWPGMQEHVK DYCRSCLFCI PRNLIGSELK VIESPWPLRS TAPWSNLQIE VVGPVTISEE GHKHVLIVAD PNTRWVEAFP LKPYTHTAVA QVLLQHVFAR WGVPVRLEAA QGPQFARHVL VSCGLALGAQ VASLSRDLQF PCLTSSGAYW EFKRALKEFI FLHGKKWAAS LPLLHLAFRA SSTDATPFKV LTGGESRLTE PLWWEMSSAN IEGLKMDVFL LQLVGELLEL HWRVADKASE KAENRRFKRE SQEKEWNVGD QVLLLSLPRN GSSAKWVGPF YIGDRLSLSL YRIWGFPTPE KLGCIYPSSL MKAFAKSGTP LSFKVLEQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NYNRIN?

The strongest Open Targets associations for NYNRIN are low density lipoprotein cholesterol measurement, neurodegenerative disease, sex hormone-binding globulin measurement, total cholesterol measurement and alkaline phosphatase measurement.

How long is the NYNRIN protein?

The Homo sapiens NYNRIN protein (UniProt Q9P2P1) is 1898 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q9P2P1 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q9P2P1 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

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