Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 (GNG13)
Homo sapiens — UniProt Q9P2W3
Data last refreshed: (UniProt release unknown)
Key facts
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 (GNG13) is a protein from Homo sapiens identified by UniProt accession Q9P2W3, 67 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q9P2W3; gene symbol GNG13.
- Organism: Homo sapiens.
- Length: 67 amino acids.
- Top disease associations (Open Targets): endometrial cancer, ovarian cancer and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 |
|---|---|
| UniProt accession | Q9P2W3 |
| Gene | GNG13 |
| Organism | Homo sapiens |
| Length | 67 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- endometrial cancer · score 0.28
- ovarian cancer · score 0.26
- mean corpuscular hemoglobin · score 0.12
- Iron deficiency anemia · score 0.11
- mean corpuscular volume · score 0.10
- MODY · score 0.06
- appendicular lean mass · score 0.06
- body height · score 0.05
- IGF-1 measurement · score 0.05
- hyperproinsulinemia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9P2W3-F1 | alphafold | PREDICTED | 88.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9P2W3.
Amino-acid sequence (67 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GNG13?
The strongest Open Targets associations for GNG13 are endometrial cancer, ovarian cancer, mean corpuscular hemoglobin, Iron deficiency anemia and mean corpuscular volume.
How long is the GNG13 protein?
The Homo sapiens GNG13 protein (UniProt Q9P2W3) is 67 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9P2W3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9P2W3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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