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Ammonium transporter Rh type C (RHCG)

Homo sapiens — UniProt Q9UBD6

Gene: RHCGHomo sapiensSwissProt reviewedTransporter

Data last refreshed: (UniProt release unknown)

Key facts

Ammonium transporter Rh type C (RHCG) is a protein from Homo sapiens identified by UniProt accession Q9UBD6, 479 residues long. MolForge cross-references it against 0 known binders and 156 disease associations.

  • UniProt accession: Q9UBD6; gene symbol RHCG.
  • Organism: Homo sapiens.
  • Length: 479 amino acids.
  • Target class: Transporter.
  • Top disease associations (Open Targets): diastolic blood pressure, systolic blood pressure and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAmmonium transporter Rh type C
UniProt accessionQ9UBD6
GeneRHCG
OrganismHomo sapiens
Length479 residues
Molecular weight—
EC numbers—
Target classTransporter (inferred from UniProt keywords / EC)
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (156)

Diseases linked to this target (Open Targets).

  • diastolic blood pressure · score 0.33
  • systolic blood pressure · score 0.33
  • neurodegenerative disease · score 0.32
  • dental caries · score 0.30
  • dentures · score 0.30
  • body weight · score 0.20
  • cutaneous melanoma · score 0.17
  • heel bone mineral density · score 0.16
  • urate measurement · score 0.16
  • lean body mass · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UBD6-F1alphafoldPREDICTED92.32—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBD6.

Amino-acid sequence (479 residues)

MAWNTNLRWR LPLTCLLLQV IMVILFGVFV RYDFEADAHW WSERTHKNLS DMENEFYYRY PSFQDVHVMV FVGFGFLMTF LQRYGFSAVG FNFLLAAFGI QWALLMQGWF HFLQDRYIVV GVENLINADF CVASVCVAFG AVLGKVSPIQ LLIMTFFQVT LFAVNEFILL NLLKVKDAGG SMTIHTFGAY FGLTVTRILY RRNLEQSKER QNSVYQSDLF AMIGTLFLWM YWPSFNSAIS YHGDSQHRAA INTYCSLAAC VLTSVAISSA LHKKGKLDMV HIQNATLAGG VAVGTAAEMM LMPYGALIIG FVCGIISTLG FVYLTPFLES RLHIQDTCGI NNLHGIPGII GGIVGAVTAA SASLEVYGKE GLVHSFDFQG FNGDWTARTQ GKFQIYGLLV TLAMALMGGI IVGLILRLPF WGQPSDENCF EDAVYWEMPE GNSTVYIPED PTFKPSGPSV PSVPMVSPLP MASSVPLVP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RHCG?

The strongest Open Targets associations for RHCG are diastolic blood pressure, systolic blood pressure, neurodegenerative disease, dental caries and dentures.

How long is the RHCG protein?

The Homo sapiens RHCG protein (UniProt Q9UBD6) is 479 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UBD6
GeneRHCG
OrganismHomo sapiens
Length479
Binders0
Diseases156
View on UniProt