COMM domain-containing protein 3 (COMMD3)
Homo sapiens — UniProt Q9UBI1
Data last refreshed: (UniProt release unknown)
Key facts
COMM domain-containing protein 3 (COMMD3) is a protein from Homo sapiens identified by UniProt accession Q9UBI1, 195 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q9UBI1; gene symbol COMMD3.
- Organism: Homo sapiens.
- Length: 195 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hepatocellular carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | COMM domain-containing protein 3 |
|---|---|
| UniProt accession | Q9UBI1 |
| Gene | COMMD3 |
| Organism | Homo sapiens |
| Length | 195 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- hepatocellular carcinoma · score 0.10
- neoplasm · score 0.08
- bladder neck obstruction · score 0.08
- body height · score 0.07
- protein measurement · score 0.06
- monocyte percentage of leukocytes · score 0.05
- lean body mass · score 0.03
- B-cell acute lymphoblastic leukemia · score 0.03
- base metabolic rate measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UBI1-F1 | alphafold | PREDICTED | 86.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBI1.
Amino-acid sequence (195 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with COMMD3?
The strongest Open Targets associations for COMMD3 are neurodegenerative disease, hepatocellular carcinoma, neoplasm, bladder neck obstruction and body height.
How long is the COMMD3 protein?
The Homo sapiens COMMD3 protein (UniProt Q9UBI1) is 195 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UBI1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UBI1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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