About Copine-7
Copine-7 (CPNE7) is a protein
from Homo sapiens identified by UniProt accession
Q9UBL6, 633 residues long.
MolForge cross-references it against 0 known binders and
151 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (151)
Diseases linked to this target (Open Targets).
- age at first sexual intercourse measurement · score 0.30
- neurodegenerative disease · score 0.27
- cognitive function measurement · score 0.25
- suntan · score 0.24
- smoking cessation · score 0.23
- tobacco smoke exposure measurement · score 0.23
- smoking behaviour measurement · score 0.23
- body mass index · score 0.22
- self reported educational attainment · score 0.19
- glioblastoma multiforme · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q9UBL6.
Amino-acid sequence (633 residues)
MSAGSERGAA ATPGGLPAPC ASKVELRLSC RHLLDRDPLT KSDPSVALLQ QAQGQWVQVG RTEVVRSSLH PVFSKVFTVD YYFEEVQRLR FEVYDTHGPS GFSCQEDDFL GGMECTLGQP AQKWLLQVVM RVSVDVLGPA GHCAKHFLCC TESSHLARTG PSFLLRYDDL CLPWATAGAV RWWTCRGGHT QGWQIVAQKK VTRPLLLKFG RNAGKSTITV IAEDISGNNG YVELSFRARK LDDKDLFSKS DPFLELYRVN DDQGLQLVYR TEVVKNNLNP VWEAFKVSLS SLCSCEETRP LKCLVWDYDS RGKHDFIGEF STTFEEMQKA FEEGQAQWDC VNPKYKQKRR SYKNSGVVVL ADLKFHRVYS FLDYIMGGCQ IHFTVAIDFT ASNGDPRNSC SLHYINPYQP NEYLKALVSV GEICQDYDSD KRFSALGFGA RIPPKYEVSH DFAINFNPED DECEGIQGVV EAYQNCLPRV QLYGPTNVAP IISKVARVAA AEESTGKASQ YYILLILTDG VVTDMADTRE AIVRASRLPM SIIIVGVGNA DFTDMQVLDG DDGVLRSPRG EPALRDIVQF VPFRELKNAS PAALAKCVLA EVPKQVVEYY SHRGLPPRSL GVPAGEASPG CTP
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