Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C)
Homo sapiens — UniProt Q9UBM8
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C (MGAT4C) is a protein from Homo sapiens identified by UniProt accession Q9UBM8, 478 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q9UBM8; gene symbol MGAT4C.
- Organism: Homo sapiens.
- Length: 478 amino acids.
- Top disease associations (Open Targets): COVID-19, antisocial behaviour measurement and attention deficit hyperactivity disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C |
|---|---|
| UniProt accession | Q9UBM8 |
| Gene | MGAT4C |
| Organism | Homo sapiens |
| Length | 478 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.37
- antisocial behaviour measurement · score 0.32
- attention deficit hyperactivity disorder · score 0.32
- substance abuse · score 0.32
- hair color · score 0.17
- diabetic nephropathy · score 0.17
- schizophrenia · score 0.17
- type 2 diabetes mellitus · score 0.17
- hair colour measurement · score 0.16
- mathematical ability · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UBM8-F1 | alphafold | PREDICTED | 87.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBM8.
Amino-acid sequence (478 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MGAT4C?
The strongest Open Targets associations for MGAT4C are COVID-19, antisocial behaviour measurement, attention deficit hyperactivity disorder, substance abuse and hair color.
How long is the MGAT4C protein?
The Homo sapiens MGAT4C protein (UniProt Q9UBM8) is 478 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UBM8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UBM8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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