Chemokine-like factor (CKLF)

About Chemokine-like factor

Chemokine-like factor (CKLF) is a protein from Homo sapiens identified by UniProt accession Q9UBR5, 152 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	Chemokine-like factor
UniProt accession	Q9UBR5
Gene	CKLF
Organism	Homo sapiens
Length	152 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (74)

Diseases linked to this target (Open Targets).

neoplasm · score 0.09
hepatocellular carcinoma · score 0.08
Stroke · score 0.08
Keloid · score 0.06
Agouti-related protein measurement · score 0.04
neuroblastoma · score 0.04
Cerebral ischemia · score 0.03
blood protein measurement · score 0.03
response to risperidone · score 0.03
psoriasis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBR5-F1	alphafold	PREDICTED	77.65	—

Amino-acid sequence (152 residues)

MDNVQPKIKH RPFCFSVKGH VKMLRLALTV TSMTFFIIAQ APEPYIVITG FEVTVILFFI LLYVLRLDRL MKWLFWPLLD IINSLVTTVF MLIVSVLALI PETTTLTVGG GVFALVTAVC CLADGALIYR KLLFNPSGPY QKKPVHEKKE VL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards