Chemokine-like factor (CKLF)
Homo sapiens — UniProt Q9UBR5
Data last refreshed: (UniProt release unknown)
Key facts
Chemokine-like factor (CKLF) is a protein from Homo sapiens identified by UniProt accession Q9UBR5, 152 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q9UBR5; gene symbol CKLF.
- Organism: Homo sapiens.
- Length: 152 amino acids.
- Top disease associations (Open Targets): neoplasm, hepatocellular carcinoma and Stroke.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chemokine-like factor |
|---|---|
| UniProt accession | Q9UBR5 |
| Gene | CKLF |
| Organism | Homo sapiens |
| Length | 152 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.09
- hepatocellular carcinoma · score 0.08
- Stroke · score 0.08
- Keloid · score 0.06
- Agouti-related protein measurement · score 0.04
- neuroblastoma · score 0.04
- Cerebral ischemia · score 0.03
- blood protein measurement · score 0.03
- response to risperidone · score 0.03
- psoriasis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UBR5-F1 | alphafold | PREDICTED | 77.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBR5.
Amino-acid sequence (152 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CKLF?
The strongest Open Targets associations for CKLF are neoplasm, hepatocellular carcinoma, Stroke, Keloid and Agouti-related protein measurement.
How long is the CKLF protein?
The Homo sapiens CKLF protein (UniProt Q9UBR5) is 152 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UBR5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UBR5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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