DnaJ homolog subfamily B member 9 (DNAJB9)

About DnaJ homolog subfamily B member 9

DnaJ homolog subfamily B member 9 (DNAJB9) is a protein from Homo sapiens identified by UniProt accession Q9UBS3, 223 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.

Target properties

Protein name	DnaJ homolog subfamily B member 9
UniProt accession	Q9UBS3
Gene	DNAJB9
Organism	Homo sapiens
Length	223 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (95)

Diseases linked to this target (Open Targets).

self reported educational attainment · score 0.28
protein measurement · score 0.21
alkaline phosphatase measurement · score 0.10
triple-negative breast cancer · score 0.06
insomnia measurement · score 0.06
hyperinsulinism due to HNF1A deficiency · score 0.04
cystic fibrosis · score 0.04
hyperinsulinemic hypoglycemia, familial, 2 · score 0.03
exercise-induced hyperinsulinism · score 0.03
hypoinsulinemic hypoglycemia and body hemihypertrophy · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UBS3-F1	alphafold	PREDICTED	65.57	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBS3.

Amino-acid sequence (223 residues)

MATPQSIFIF AICILMITEL ILASKSYYDI LGVPKSASER QIKKAFHKLA MKYHPDKNKS PDAEAKFREI AEAYETLSDA NRRKEYDTLG HSAFTSGKGQ RGSGSSFEQS FNFNFDDLFK DFGFFGQNQN TGSKKRFENH FQTRQDGGSS RQRHHFQEFS FGGGLFDDMF EDMEKMFSFS GFDSTNQHTV QTENRFHGSS KHCRTVTQRR GNMVTTYTDC SGQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards