SUN domain-containing ossification factor (SUCO)
Homo sapiens — UniProt Q9UBS9
Data last refreshed: (UniProt release unknown)
Key facts
SUN domain-containing ossification factor (SUCO) is a protein from Homo sapiens identified by UniProt accession Q9UBS9, 1254 residues long. MolForge cross-references it against 0 known binders and 154 disease associations.
- UniProt accession: Q9UBS9; gene symbol SUCO.
- Organism: Homo sapiens.
- Length: 1254 amino acids.
- Top disease associations (Open Targets): osteogenesis imperfecta, Skeletal dysplasia and skeletal dysplasia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SUN domain-containing ossification factor |
|---|---|
| UniProt accession | Q9UBS9 |
| Gene | SUCO |
| Organism | Homo sapiens |
| Length | 1254 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (154)
Diseases linked to this target (Open Targets).
- osteogenesis imperfecta · score 0.23
- Skeletal dysplasia · score 0.23
- skeletal dysplasia · score 0.23
- Osteopenia · score 0.23
- eustachian tube disease · score 0.08
- eosinophil count · score 0.08
- hepatocellular carcinoma · score 0.08
- appendicular lean mass · score 0.07
- allergic disease · score 0.07
- body height · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UBS9-F1 | alphafold | PREDICTED | 52.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBS9.
Amino-acid sequence (1254 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SUCO?
The strongest Open Targets associations for SUCO are osteogenesis imperfecta, Skeletal dysplasia, skeletal dysplasia, Osteopenia and eustachian tube disease.
How long is the SUCO protein?
The Homo sapiens SUCO protein (UniProt Q9UBS9) is 1254 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UBS9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UBS9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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