Zinc finger MYM-type protein 2 (ZMYM2)
Homo sapiens — UniProt Q9UBW7
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger MYM-type protein 2 (ZMYM2) is a protein from Homo sapiens identified by UniProt accession Q9UBW7, 1377 residues long. MolForge cross-references it against 0 known binders and 184 disease associations.
- UniProt accession: Q9UBW7; gene symbol ZMYM2.
- Organism: Homo sapiens.
- Length: 1377 amino acids.
- Top disease associations (Open Targets): neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities, cancer and congenital anomaly of kidney and urinary tract.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger MYM-type protein 2 |
|---|---|
| UniProt accession | Q9UBW7 |
| Gene | ZMYM2 |
| Organism | Homo sapiens |
| Length | 1377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (184)
Diseases linked to this target (Open Targets).
- neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities · score 0.71
- cancer · score 0.60
- congenital anomaly of kidney and urinary tract · score 0.55
- congenital hydronephrosis · score 0.55
- genetic disorder · score 0.53
- acute lymphoblastic leukemia · score 0.49
- body mass index · score 0.48
- myelodysplastic syndrome · score 0.46
- leukemia · score 0.46
- body fat percentage · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UBW7-F1 | alphafold | PREDICTED | 60.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UBW7.
Amino-acid sequence (1377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZMYM2?
The strongest Open Targets associations for ZMYM2 are neurodevelopmental-craniofacial syndrome with variable renal and cardiac abnormalities, cancer, congenital anomaly of kidney and urinary tract, congenital hydronephrosis and genetic disorder.
How long is the ZMYM2 protein?
The Homo sapiens ZMYM2 protein (UniProt Q9UBW7) is 1377 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UBW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UBW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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