Serine/threonine-protein kinase 17A (STK17A)
Homo sapiens — UniProt Q9UEE5
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase 17A (STK17A) is a protein from Homo sapiens identified by UniProt accession Q9UEE5, 414 residues long. MolForge cross-references it against 13 known binders and 56 disease associations.
- UniProt accession: Q9UEE5; gene symbol STK17A.
- Organism: Homo sapiens.
- Length: 414 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase 17A |
|---|---|
| UniProt accession | Q9UEE5 |
| Gene | STK17A |
| Organism | Homo sapiens |
| Length | 414 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.43
- mean corpuscular hemoglobin concentration · score 0.40
- mean corpuscular hemoglobin · score 0.38
- mean reticulocyte volume · score 0.35
- neurodegenerative disease · score 0.30
- brain volume measurement · score 0.25
- urate measurement · score 0.21
- reticulocyte count · score 0.14
- glioblastoma multiforme · score 0.08
- brain measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UEE5-F1 | alphafold | PREDICTED | 75.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UEE5.
Amino-acid sequence (414 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STK17A?
The strongest Open Targets associations for STK17A are mean corpuscular volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, mean reticulocyte volume and neurodegenerative disease.
How long is the STK17A protein?
The Homo sapiens STK17A protein (UniProt Q9UEE5) is 414 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UEE5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UEE5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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