Zinc finger protein 629 (ZNF629)
Homo sapiens — UniProt Q9UEG4
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 629 (ZNF629) is a protein from Homo sapiens identified by UniProt accession Q9UEG4, 869 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9UEG4; gene symbol ZNF629.
- Organism: Homo sapiens.
- Length: 869 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, multiple sclerosis and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 629 |
|---|---|
| UniProt accession | Q9UEG4 |
| Gene | ZNF629 |
| Organism | Homo sapiens |
| Length | 869 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- multiple sclerosis · score 0.37
- Parkinson disease · score 0.37
- Alzheimer disease · score 0.37
- lysosomal storage disease · score 0.37
- sex hormone-binding globulin measurement · score 0.08
- alkaline phosphatase measurement · score 0.03
- C-reactive protein measurement · score 0.02
- platelet count · score 0.02
- acute lymphoblastic leukemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UEG4-F1 | alphafold | PREDICTED | 63.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UEG4.
Amino-acid sequence (869 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF629?
The strongest Open Targets associations for ZNF629 are neurodegenerative disease, multiple sclerosis, Parkinson disease, Alzheimer disease and lysosomal storage disease.
How long is the ZNF629 protein?
The Homo sapiens ZNF629 protein (UniProt Q9UEG4) is 869 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UEG4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UEG4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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