Death domain-associated protein 6 (DAXX)
Homo sapiens — UniProt Q9UER7
Data last refreshed: (UniProt release unknown)
Key facts
Death domain-associated protein 6 (DAXX) is a protein from Homo sapiens identified by UniProt accession Q9UER7, 740 residues long. MolForge cross-references it against 0 known binders and 272 disease associations.
- UniProt accession: Q9UER7; gene symbol DAXX.
- Organism: Homo sapiens.
- Length: 740 amino acids.
- Top disease associations (Open Targets): pancreatic neuroendocrine tumor, viral disease and cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Death domain-associated protein 6 |
|---|---|
| UniProt accession | Q9UER7 |
| Gene | DAXX |
| Organism | Homo sapiens |
| Length | 740 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (272)
Diseases linked to this target (Open Targets).
- pancreatic neuroendocrine tumor · score 0.56
- viral disease · score 0.47
- cancer · score 0.39
- melanoma · score 0.37
- Thyroid Gland Oncocytic Follicular Carcinoma · score 0.37
- Non-Functional Pancreatic Neuroendocrine Tumor · score 0.37
- cutaneous melanoma · score 0.37
- Endometrial Endometrioid Adenocarcinoma · score 0.37
- Transitional Meningioma · score 0.37
- skin squamous cell carcinoma · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UER7-F1 | alphafold | PREDICTED | 62.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UER7.
Amino-acid sequence (740 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DAXX?
The strongest Open Targets associations for DAXX are pancreatic neuroendocrine tumor, viral disease, cancer, melanoma and Thyroid Gland Oncocytic Follicular Carcinoma.
How long is the DAXX protein?
The Homo sapiens DAXX protein (UniProt Q9UER7) is 740 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UER7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UER7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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