Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B)
Homo sapiens — UniProt Q9UEU0
Data last refreshed: (UniProt release unknown)
Key facts
Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B) is a protein from Homo sapiens identified by UniProt accession Q9UEU0, 232 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9UEU0; gene symbol VTI1B.
- Organism: Homo sapiens.
- Length: 232 amino acids.
- Top disease associations (Open Targets): breast adenocarcinoma, creatinine measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicle transport through interaction with t-SNAREs homolog 1B |
|---|---|
| UniProt accession | Q9UEU0 |
| Gene | VTI1B |
| Organism | Homo sapiens |
| Length | 232 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- breast adenocarcinoma · score 0.25
- creatinine measurement · score 0.16
- glomerular filtration rate · score 0.13
- gallbladder disease · score 0.04
- PHF-tau measurement · score 0.04
- Isolated polycystic liver disease · score 0.04
- low phospholipid associated cholelithiasis · score 0.04
- sclerosing cholangitis · score 0.03
- benign recurrent intrahepatic cholestasis · score 0.03
- cholelithiasis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UEU0-F1 | alphafold | PREDICTED | 83.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UEU0.
Amino-acid sequence (232 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with VTI1B?
The strongest Open Targets associations for VTI1B are breast adenocarcinoma, creatinine measurement, glomerular filtration rate, gallbladder disease and PHF-tau measurement.
How long is the VTI1B protein?
The Homo sapiens VTI1B protein (UniProt Q9UEU0) is 232 amino acids long.
Browse: Targets: V · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UEU0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UEU0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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