DnaJ homolog subfamily C member 5B (DNAJC5B)
Homo sapiens — UniProt Q9UF47
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 5B (DNAJC5B) is a protein from Homo sapiens identified by UniProt accession Q9UF47, 199 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.
- UniProt accession: Q9UF47; gene symbol DNAJC5B.
- Organism: Homo sapiens.
- Length: 199 amino acids.
- Top disease associations (Open Targets): eosinophil count, mean corpuscular volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 5B |
|---|---|
| UniProt accession | Q9UF47 |
| Gene | DNAJC5B |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.40
- mean corpuscular volume · score 0.40
- platelet count · score 0.40
- mean corpuscular hemoglobin concentration · score 0.38
- mean corpuscular hemoglobin · score 0.37
- erythrocyte count · score 0.36
- platelet crit · score 0.33
- body height · score 0.33
- eosinophil percentage of leukocytes · score 0.32
- blood urea nitrogen measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UF47-F1 | alphafold | PREDICTED | 73.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UF47.
Amino-acid sequence (199 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC5B?
The strongest Open Targets associations for DNAJC5B are eosinophil count, mean corpuscular volume, platelet count, mean corpuscular hemoglobin concentration and mean corpuscular hemoglobin.
How long is the DNAJC5B protein?
The Homo sapiens DNAJC5B protein (UniProt Q9UF47) is 199 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UF47 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UF47 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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