F-box/LRR-repeat protein 17 (FBXL17)
Homo sapiens — UniProt Q9UF56
Data last refreshed: (UniProt release unknown)
Key facts
F-box/LRR-repeat protein 17 (FBXL17) is a protein from Homo sapiens identified by UniProt accession Q9UF56, 701 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q9UF56; gene symbol FBXL17.
- Organism: Homo sapiens.
- Length: 701 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, body mass index and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box/LRR-repeat protein 17 |
|---|---|
| UniProt accession | Q9UF56 |
| Gene | FBXL17 |
| Organism | Homo sapiens |
| Length | 701 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.42
- body mass index · score 0.39
- body fat percentage · score 0.38
- self reported educational attainment · score 0.37
- smoking status measurement · score 0.33
- mean corpuscular hemoglobin concentration · score 0.32
- body weight · score 0.31
- cortical surface area measurement · score 0.31
- eosinophil count · score 0.31
- neuroticism measurement · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UF56-F1 | alphafold | PREDICTED | 68.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UF56.
Amino-acid sequence (701 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXL17?
The strongest Open Targets associations for FBXL17 are mean corpuscular volume, body mass index, body fat percentage, self reported educational attainment and smoking status measurement.
How long is the FBXL17 protein?
The Homo sapiens FBXL17 protein (UniProt Q9UF56) is 701 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UF56 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UF56 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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