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Zinc finger and BTB domain-containing protein 47 (ZBTB47)

Homo sapiens — UniProt Q9UFB7

Gene: ZBTB47Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger and BTB domain-containing protein 47 (ZBTB47) is a protein from Homo sapiens identified by UniProt accession Q9UFB7, 747 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

  • UniProt accession: Q9UFB7; gene symbol ZBTB47.
  • Organism: Homo sapiens.
  • Length: 747 amino acids.
  • Top disease associations (Open Targets): Neurodevelopmental disorder, neurodegenerative disease and Seizure.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger and BTB domain-containing protein 47
UniProt accessionQ9UFB7
GeneZBTB47
OrganismHomo sapiens
Length747 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (19)

Diseases linked to this target (Open Targets).

  • Neurodevelopmental disorder · score 0.37
  • neurodegenerative disease · score 0.24
  • Seizure · score 0.12
  • Neurodevelopmental delay · score 0.12
  • pancreatic adenocarcinoma · score 0.03
  • protein measurement · score 0.03
  • fetal genotype effect measurement · score 0.03
  • C-C motif chemokine 17 measurement · score 0.02
  • monokine induced by gamma interferon measurement · score 0.02
  • CCL19 measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UFB7-F1alphafoldPREDICTED53.31—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UFB7.

Amino-acid sequence (747 residues)

MGRLNEQRLF QPDLCDVDLV LVPQRSVFPA HKGVLAAYSQ FFHSLFTQNK QLQRVELSLE ALAPGGLQQI LNFIYTSKLL VNAANVHEVL SAASLLQMAD IAASCQELLD ARSLGPPGPG TVALAQPAAS CTPAAPPYYC DIKQEADTPG LPKIYAREGP DPYSVRVEDG AGTAGGTVPA TIGPAQPFFK EEKEGGVEEA GGPPASLCKL EGGEELEEEL GGSGTYSRRE QSQIIVEVNL NNQTLHVSTG PEGKPGAGPS PATVVLGRED GLQRHSDEEE EDDEEEEEEE EEEEGGGSGR EEEEEEEGGS QGEEEEEEED GHSEQEEEEE EEEEEGPSEQ DQESSEEEEG EEGEAGGKQG PRGSRSSRAD PPPHSHMATR SRENARRRGT PEPEEAGRRG GKRPKPPPGV ASASARGPPA TDGLGAKVKL EEKQHHPCQK CPRVFNNRWY LEKHMNVTHS RMQICDQCGK RFLLESELLL HRQTDCERNI QCVTCGKAFK KLWSLHEHNK IVHGYAEKKF SCEICEKKFY TMAHVRKHMV AHTKDMPFTC ETCGKSFKRS MSLKVHSLQH SGEKPFRCEN CNERFQYKYQ LRSHMSIHIG HKQFMCQWCG KDFNMKQYFD EHMKTHTGEK PYICEICGKS FTSRPNMKRH RRTHTGEKPY PCDVCGQRFR FSNMLKAHKE KCFRVSHTLA GDGVPAAPGL PPTQPQAHAL PLLPGLPQTL PPPPHLPPPP PLFPTTASPG GRMNANN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZBTB47?

The strongest Open Targets associations for ZBTB47 are Neurodevelopmental disorder, neurodegenerative disease, Seizure, Neurodevelopmental delay and pancreatic adenocarcinoma.

How long is the ZBTB47 protein?

The Homo sapiens ZBTB47 protein (UniProt Q9UFB7) is 747 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

Explore Zinc finger and BTB domain-containing protein 47 with MolForge

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Quick facts

UniProtQ9UFB7
GeneZBTB47
OrganismHomo sapiens
Length747
Binders0
Diseases19
View on UniProt