UPF0449 protein C19orf25 (C19orf25)
Homo sapiens — UniProt Q9UFG5
Data last refreshed: (UniProt release unknown)
Key facts
UPF0449 protein C19orf25 (C19orf25) is a protein from Homo sapiens identified by UniProt accession Q9UFG5, 118 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q9UFG5; gene symbol C19orf25.
- Organism: Homo sapiens.
- Length: 118 amino acids.
- Top disease associations (Open Targets): complex cortical dysplasia with other brain malformations, Sotos syndrome and intellectual developmental disorder, autosomal recessive 74.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0449 protein C19orf25 |
|---|---|
| UniProt accession | Q9UFG5 |
| Gene | C19orf25 |
| Organism | Homo sapiens |
| Length | 118 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- complex cortical dysplasia with other brain malformations · score 0.47
- Sotos syndrome · score 0.45
- intellectual developmental disorder, autosomal recessive 74 · score 0.45
- genetic disorder · score 0.19
- Seizure · score 0.15
- breast ductal adenocarcinoma · score 0.11
- cancer · score 0.01
- Duane retraction syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UFG5-F1 | alphafold | PREDICTED | 83.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UFG5.
Amino-acid sequence (118 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C19orf25?
The strongest Open Targets associations for C19orf25 are complex cortical dysplasia with other brain malformations, Sotos syndrome, intellectual developmental disorder, autosomal recessive 74, genetic disorder and Seizure.
How long is the C19orf25 protein?
The Homo sapiens C19orf25 protein (UniProt Q9UFG5) is 118 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UFG5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UFG5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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