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Protein NipSnap homolog 3A (NIPSNAP3A)

Homo sapiens — UniProt Q9UFN0

Gene: NIPSNAP3AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein NipSnap homolog 3A (NIPSNAP3A) is a protein from Homo sapiens identified by UniProt accession Q9UFN0, 247 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

  • UniProt accession: Q9UFN0; gene symbol NIPSNAP3A.
  • Organism: Homo sapiens.
  • Length: 247 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, 3-hydroxyisobutyrate measurement and coronary artery disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein NipSnap homolog 3A
UniProt accessionQ9UFN0
GeneNIPSNAP3A
OrganismHomo sapiens
Length247 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (36)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.41
  • 3-hydroxyisobutyrate measurement · score 0.31
  • coronary artery disease · score 0.09
  • low density lipoprotein cholesterol measurement · score 0.08
  • gut microbiome measurement · score 0.08
  • high density lipoprotein cholesterol measurement · score 0.07
  • reticulocyte count · score 0.07
  • total cholesterol measurement · score 0.07
  • apolipoprotein A 1 measurement · score 0.06
  • Okt4 epitope deficiency · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UFN0-F1alphafoldPREDICTED90.45—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UFN0.

Amino-acid sequence (247 residues)

MLVLRSALTR ALASRTLAPQ MCSSFATGPR QYDGIFYEFR SYYLKPSKMN EFLENFEKNA HLRTAHSELV GYWSVEFGGR MNTVFHIWKY DNFAHRTEVR KALAKDKEWQ EQFLIPNLAL IDKQESEITY LVPWCKLEKP PKEGVYELAT FQMKPGGPAL WGDAFKRAVH AHVNLGYTKL VGVFHTEYGA LNRVHVLWWN ESADSRAAGR HKSHEDPRVV AAVRESVNYL VSQQNMLLIP TSFSPLK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NIPSNAP3A?

The strongest Open Targets associations for NIPSNAP3A are neurodegenerative disease, 3-hydroxyisobutyrate measurement, coronary artery disease, low density lipoprotein cholesterol measurement and gut microbiome measurement.

How long is the NIPSNAP3A protein?

The Homo sapiens NIPSNAP3A protein (UniProt Q9UFN0) is 247 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UFN0
GeneNIPSNAP3A
OrganismHomo sapiens
Length247
Binders0
Diseases36
View on UniProt