CGG triplet repeat-binding protein 1 (CGGBP1)
Homo sapiens — UniProt Q9UFW8
Data last refreshed: (UniProt release unknown)
Key facts
CGG triplet repeat-binding protein 1 (CGGBP1) is a protein from Homo sapiens identified by UniProt accession Q9UFW8, 167 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9UFW8; gene symbol CGGBP1.
- Organism: Homo sapiens.
- Length: 167 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, erythrocyte count and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CGG triplet repeat-binding protein 1 |
|---|---|
| UniProt accession | Q9UFW8 |
| Gene | CGGBP1 |
| Organism | Homo sapiens |
| Length | 167 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- erythrocyte count · score 0.33
- mean corpuscular volume · score 0.31
- body mass index · score 0.30
- red blood cell density measurement · score 0.28
- lean body mass · score 0.25
- reticulocyte count · score 0.23
- mean corpuscular hemoglobin · score 0.22
- smoking status measurement · score 0.22
- testosterone measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UFW8-F1 | alphafold | PREDICTED | 76.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UFW8.
Amino-acid sequence (167 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CGGBP1?
The strongest Open Targets associations for CGGBP1 are neurodegenerative disease, erythrocyte count, mean corpuscular volume, body mass index and red blood cell density measurement.
How long is the CGGBP1 protein?
The Homo sapiens CGGBP1 protein (UniProt Q9UFW8) is 167 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UFW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UFW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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