About CGG triplet repeat-binding protein 1
CGG triplet repeat-binding protein 1 (CGGBP1) is a protein
from Homo sapiens identified by UniProt accession
Q9UFW8, 167 residues long.
MolForge cross-references it against 0 known binders and
52 disease associations.
Target properties
| Protein name | CGG triplet repeat-binding protein 1 |
|---|
| UniProt accession | Q9UFW8 |
|---|
| Gene | CGGBP1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 167 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (52)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- erythrocyte count · score 0.33
- mean corpuscular volume · score 0.31
- body mass index · score 0.30
- red blood cell density measurement · score 0.28
- lean body mass · score 0.25
- reticulocyte count · score 0.23
- mean corpuscular hemoglobin · score 0.22
- smoking status measurement · score 0.22
- testosterone measurement · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9UFW8-F1 | alphafold | PREDICTED | 76.33 | — |
Amino-acid sequence (167 residues)
MERFVVTAPP ARNRSKTALY VTPLDRVTEF GGELHEDGGK LFCTSCNVVL NHVRKSAISD HLKSKTHTKR KAEFEEQNVR KKQRPLTASL QCNSTAQTEK VSVIQDFVKM CLEANIPLEK ADHPAVRAFL SRHVKNGGSI PKSDQLRRAY LPDGYENENQ LLNSQDC
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