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Inositol oxygenase (MIOX)

Homo sapiens — UniProt Q9UGB7

Gene: MIOXHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Inositol oxygenase (MIOX) is a protein from Homo sapiens identified by UniProt accession Q9UGB7, 285 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

  • UniProt accession: Q9UGB7; gene symbol MIOX.
  • Organism: Homo sapiens.
  • Length: 285 amino acids.
  • Top disease associations (Open Targets): gut microbiome measurement, nonpapillary renal cell carcinoma and low density lipoprotein cholesterol measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameInositol oxygenase
UniProt accessionQ9UGB7
GeneMIOX
OrganismHomo sapiens
Length285 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (63)

Diseases linked to this target (Open Targets).

  • gut microbiome measurement · score 0.09
  • nonpapillary renal cell carcinoma · score 0.07
  • low density lipoprotein cholesterol measurement · score 0.06
  • mean corpuscular volume · score 0.05
  • apolipoprotein B measurement · score 0.05
  • mean reticulocyte volume · score 0.05
  • vitamin D measurement · score 0.05
  • blood protein measurement · score 0.05
  • drug use measurement · score 0.04
  • non-small cell lung carcinoma · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UGB7-F1alphafoldPREDICTED93.47—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UGB7.

Amino-acid sequence (285 residues)

MKVTVGPDPS LVYRPDVDPE VAKDKASFRN YTSGPLLDRV FTTYKLMHTH QTVDFVRSKH AQFGGFSYKK MTVMEAVDLL DGLVDESDPD VDFPNSFHAF QTAEGIRKAH PDKDWFHLVG LLHDLGKVLA LFGEPQWAVV GDTFPVGCRP QASVVFCDST FQDNPDLQDP RYSTELGMYQ PHCGLDRVLM SWGHDEYMYQ VMKFNKFSLP PEAFYMIRFH SFYPWHTGRD YQQLCSQQDL AMLPWVREFN KFDLYTKCPD LPDVDKLRPY YQGLIDKYCP GILSW

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MIOX?

The strongest Open Targets associations for MIOX are gut microbiome measurement, nonpapillary renal cell carcinoma, low density lipoprotein cholesterol measurement, mean corpuscular volume and apolipoprotein B measurement.

How long is the MIOX protein?

The Homo sapiens MIOX protein (UniProt Q9UGB7) is 285 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UGB7
GeneMIOX
OrganismHomo sapiens
Length285
Binders0
Diseases63
View on UniProt