Armadillo repeat-containing X-linked protein 3 (ARMCX3)
Homo sapiens — UniProt Q9UH62
Data last refreshed: (UniProt release unknown)
Key facts
Armadillo repeat-containing X-linked protein 3 (ARMCX3) is a protein from Homo sapiens identified by UniProt accession Q9UH62, 379 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q9UH62; gene symbol ARMCX3.
- Organism: Homo sapiens.
- Length: 379 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, neoplasm and Obesity.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Armadillo repeat-containing X-linked protein 3 |
|---|---|
| UniProt accession | Q9UH62 |
| Gene | ARMCX3 |
| Organism | Homo sapiens |
| Length | 379 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.07
- neoplasm · score 0.05
- Obesity · score 0.03
- non-alcoholic fatty liver disease · score 0.02
- juvenile dermatomyositis · score 0.01
- psoriasis · score 0.01
- osteoporosis-pseudoglioma syndrome · score 0.01
- Kidney Oncocytoma · score 0.01
- Hepatic steatosis · score 0.01
- hepatitis B virus induced hepatocellular carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UH62-F1 | alphafold | PREDICTED | 76.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UH62.
Amino-acid sequence (379 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARMCX3?
The strongest Open Targets associations for ARMCX3 are hepatocellular carcinoma, neoplasm, Obesity, non-alcoholic fatty liver disease and juvenile dermatomyositis.
How long is the ARMCX3 protein?
The Homo sapiens ARMCX3 protein (UniProt Q9UH62) is 379 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UH62 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UH62 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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