Switch-associated protein 70 (SWAP70)
Homo sapiens — UniProt Q9UH65
Data last refreshed: (UniProt release unknown)
Key facts
Switch-associated protein 70 (SWAP70) is a protein from Homo sapiens identified by UniProt accession Q9UH65, 585 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.
- UniProt accession: Q9UH65; gene symbol SWAP70.
- Organism: Homo sapiens.
- Length: 585 amino acids.
- Top disease associations (Open Targets): reticulocyte count, diastolic blood pressure and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Switch-associated protein 70 |
|---|---|
| UniProt accession | Q9UH65 |
| Gene | SWAP70 |
| Organism | Homo sapiens |
| Length | 585 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (130)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.52
- diastolic blood pressure · score 0.51
- systolic blood pressure · score 0.51
- mean corpuscular volume · score 0.51
- mean corpuscular hemoglobin concentration · score 0.50
- Red cell distribution width · score 0.50
- coronary artery disease · score 0.50
- hypertension · score 0.48
- HbA1c measurement · score 0.48
- mean arterial pressure · score 0.46
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UH65-F1 | alphafold | PREDICTED | 81.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UH65.
Amino-acid sequence (585 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SWAP70?
The strongest Open Targets associations for SWAP70 are reticulocyte count, diastolic blood pressure, systolic blood pressure, mean corpuscular volume and mean corpuscular hemoglobin concentration.
How long is the SWAP70 protein?
The Homo sapiens SWAP70 protein (UniProt Q9UH65) is 585 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UH65 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UH65 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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