Transcription factor COE1 (EBF1)
Homo sapiens — UniProt Q9UH73
Data last refreshed: (UniProt release unknown)
Key facts
Transcription factor COE1 (EBF1) is a protein from Homo sapiens identified by UniProt accession Q9UH73, 591 residues long. MolForge cross-references it against 0 known binders and 526 disease associations.
- UniProt accession: Q9UH73; gene symbol EBF1.
- Organism: Homo sapiens.
- Length: 591 amino acids.
- Top disease associations (Open Targets): diffuse large B-cell lymphoma, diastolic blood pressure and breast carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription factor COE1 |
|---|---|
| UniProt accession | Q9UH73 |
| Gene | EBF1 |
| Organism | Homo sapiens |
| Length | 591 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (526)
Diseases linked to this target (Open Targets).
- diffuse large B-cell lymphoma · score 0.51
- diastolic blood pressure · score 0.50
- breast carcinoma · score 0.50
- systolic blood pressure · score 0.50
- neurodegenerative disease · score 0.49
- lymphocyte count · score 0.48
- balding measurement · score 0.47
- body mass index · score 0.46
- heel bone mineral density · score 0.46
- vital capacity · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UH73-F1 | alphafold | PREDICTED | 70.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UH73.
Amino-acid sequence (591 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EBF1?
The strongest Open Targets associations for EBF1 are diffuse large B-cell lymphoma, diastolic blood pressure, breast carcinoma, systolic blood pressure and neurodegenerative disease.
How long is the EBF1 protein?
The Homo sapiens EBF1 protein (UniProt Q9UH73) is 591 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UH73 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UH73 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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