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Max-like protein X (MLX)

Homo sapiens — UniProt Q9UH92

Gene: MLXHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Max-like protein X (MLX) is a protein from Homo sapiens identified by UniProt accession Q9UH92, 298 residues long. MolForge cross-references it against 0 known binders and 188 disease associations.

  • UniProt accession: Q9UH92; gene symbol MLX.
  • Organism: Homo sapiens.
  • Length: 298 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, 46,XX gonadal dysgenesis and C-reactive protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMax-like protein X
UniProt accessionQ9UH92
GeneMLX
OrganismHomo sapiens
Length298 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (188)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.46
  • 46,XX gonadal dysgenesis · score 0.42
  • C-reactive protein measurement · score 0.21
  • type 2 diabetes mellitus · score 0.20
  • leukocyte count · score 0.20
  • high density lipoprotein cholesterol measurement · score 0.20
  • apolipoprotein A 1 measurement · score 0.19
  • serum gamma-glutamyl transferase measurement · score 0.18
  • BMI-adjusted waist-hip ratio · score 0.16
  • monocyte count · score 0.16

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UH92-F1alphafoldPREDICTED72.38—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UH92.

Amino-acid sequence (298 residues)

MTEPGASPED PWVKASPVGA HAGEGRAGRA RARRGAGRRG ASLLSPKSPT LSVPRGCRED SSHPACAKVE YAYSDNSLDP GLFVESTRKG SVVSRANSIG STSASSVPNT DDEDSDYHQE AYKESYKDRR RRAHTQAEQK RRDAIKRGYD DLQTIVPTCQ QQDFSIGSQK LSKAIVLQKT IDYIQFLHKE KKKQEEEVST LRKDVTALKI MKVNYEQIVK AHQDNPHEGE DQVSDQVKFN VFQGIMDSLF QSFNASISVA SFQELSACVF SWIEEHCKPQ TLREIVIGVL HQLKNQLY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MLX?

The strongest Open Targets associations for MLX are neurodegenerative disease, 46,XX gonadal dysgenesis, C-reactive protein measurement, type 2 diabetes mellitus and leukocyte count.

How long is the MLX protein?

The Homo sapiens MLX protein (UniProt Q9UH92) is 298 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UH92
GeneMLX
OrganismHomo sapiens
Length298
Binders0
Diseases188
View on UniProt