Probable ribosome biogenesis protein RLP24 (RSL24D1)

About Probable ribosome biogenesis protein RLP24

Probable ribosome biogenesis protein RLP24 (RSL24D1) is a protein from Homo sapiens identified by UniProt accession Q9UHA3, 163 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Probable ribosome biogenesis protein RLP24
UniProt accession	Q9UHA3
Gene	RSL24D1
Organism	Homo sapiens
Length	163 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
Parkinson disease · score 0.45
lysosomal storage disease · score 0.45
multiple sclerosis · score 0.45
Alzheimer disease · score 0.45
hair colour measurement · score 0.20
interstitial nephritis · score 0.08
renal tubule disease · score 0.08
drug use measurement · score 0.05
neoplasm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UHA3-F1	alphafold	PREDICTED	91.22	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHA3.

Amino-acid sequence (163 residues)

MRIEKCYFCS GPIYPGHGMM FVRNDCKVFR FCKSKCHKNF KKKRNPRKVR WTKAFRKAAG KELTVDNSFE FEKRRNEPIK YQRELWNKTI DAMKRVEEIK QKRQAKFIMN RLKKNKELQK VQDIKEVKQN IHLIRAPLAG KGKQLEEKMV QQLQEDVDME DAP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards