STEAP1 protein (STEAP1)
Homo sapiens — UniProt Q9UHE8
Data last refreshed: (UniProt release unknown)
Key facts
STEAP1 protein (STEAP1) is a protein from Homo sapiens identified by UniProt accession Q9UHE8, 339 residues long. MolForge cross-references it against 0 known binders and 115 disease associations.
- UniProt accession: Q9UHE8; gene symbol STEAP1.
- Organism: Homo sapiens.
- Length: 339 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, type 2 diabetes mellitus and arterial stiffness measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | STEAP1 protein |
|---|---|
| UniProt accession | Q9UHE8 |
| Gene | STEAP1 |
| Organism | Homo sapiens |
| Length | 339 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (115)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.31
- type 2 diabetes mellitus · score 0.31
- arterial stiffness measurement · score 0.29
- neurodegenerative disease · score 0.27
- pulse pressure measurement · score 0.24
- coffee consumption measurement · score 0.21
- coffee consumption · score 0.21
- glucose measurement · score 0.20
- type 1 diabetes mellitus · score 0.16
- neoplasm · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHE8-F1 | alphafold | PREDICTED | 84.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHE8.
Amino-acid sequence (339 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STEAP1?
The strongest Open Targets associations for STEAP1 are diastolic blood pressure, type 2 diabetes mellitus, arterial stiffness measurement, neurodegenerative disease and pulse pressure measurement.
How long is the STEAP1 protein?
The Homo sapiens STEAP1 protein (UniProt Q9UHE8) is 339 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHE8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHE8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.