Epidermal growth factor-like protein 7 (EGFL7)
Homo sapiens — UniProt Q9UHF1
Data last refreshed: (UniProt release unknown)
Key facts
Epidermal growth factor-like protein 7 (EGFL7) is a protein from Homo sapiens identified by UniProt accession Q9UHF1, 273 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.
- UniProt accession: Q9UHF1; gene symbol EGFL7.
- Organism: Homo sapiens.
- Length: 273 amino acids.
- Top disease associations (Open Targets): mean reticulocyte volume, neurodegenerative disease and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Epidermal growth factor-like protein 7 |
|---|---|
| UniProt accession | Q9UHF1 |
| Gene | EGFL7 |
| Organism | Homo sapiens |
| Length | 273 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (131)
Diseases linked to this target (Open Targets).
- mean reticulocyte volume · score 0.32
- neurodegenerative disease · score 0.29
- mean corpuscular hemoglobin · score 0.19
- diastolic blood pressure · score 0.15
- systolic blood pressure · score 0.13
- reticulocyte measurement · score 0.12
- hepatocellular carcinoma · score 0.11
- neoplasm · score 0.11
- neurofibrillary tangles measurement · score 0.10
- visual perception measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHF1-F1 | alphafold | PREDICTED | 75.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHF1.
Amino-acid sequence (273 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EGFL7?
The strongest Open Targets associations for EGFL7 are mean reticulocyte volume, neurodegenerative disease, mean corpuscular hemoglobin, diastolic blood pressure and systolic blood pressure.
How long is the EGFL7 protein?
The Homo sapiens EGFL7 protein (UniProt Q9UHF1) is 273 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHF1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHF1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.