Interleukin-20 receptor subunit alpha (IL20RA)
Homo sapiens — UniProt Q9UHF4
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-20 receptor subunit alpha (IL20RA) is a protein from Homo sapiens identified by UniProt accession Q9UHF4, 553 residues long. MolForge cross-references it against 0 known binders and 163 disease associations.
- UniProt accession: Q9UHF4; gene symbol IL20RA.
- Organism: Homo sapiens.
- Length: 553 amino acids.
- Top disease associations (Open Targets): type 2 diabetes mellitus, Drugs used in diabetes use measurement and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-20 receptor subunit alpha |
|---|---|
| UniProt accession | Q9UHF4 |
| Gene | IL20RA |
| Organism | Homo sapiens |
| Length | 553 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (163)
Diseases linked to this target (Open Targets).
- type 2 diabetes mellitus · score 0.33
- Drugs used in diabetes use measurement · score 0.27
- HbA1c measurement · score 0.24
- hemoglobin A1 measurement · score 0.21
- multiple sclerosis · score 0.11
- neoplasm · score 0.08
- calcium measurement · score 0.07
- hemoglobin E-beta-thalassemia syndrome · score 0.06
- melorheostosis · score 0.06
- IRIDA syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHF4-F1 | alphafold | PREDICTED | 62.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHF4.
Amino-acid sequence (553 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL20RA?
The strongest Open Targets associations for IL20RA are type 2 diabetes mellitus, Drugs used in diabetes use measurement, HbA1c measurement, hemoglobin A1 measurement and multiple sclerosis.
How long is the IL20RA protein?
The Homo sapiens IL20RA protein (UniProt Q9UHF4) is 553 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHF4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHF4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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