Interleukin-17B (IL17B)
Homo sapiens — UniProt Q9UHF5
Data last refreshed: (UniProt release unknown)
Key facts
Interleukin-17B (IL17B) is a protein from Homo sapiens identified by UniProt accession Q9UHF5, 180 residues long. MolForge cross-references it against 0 known binders and 172 disease associations.
- UniProt accession: Q9UHF5; gene symbol IL17B.
- Organism: Homo sapiens.
- Length: 180 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and bilirubin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Interleukin-17B |
|---|---|
| UniProt accession | Q9UHF5 |
| Gene | IL17B |
| Organism | Homo sapiens |
| Length | 180 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (172)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.29
- bone quantitative ultrasound measurement · score 0.23
- bilirubin measurement · score 0.20
- diet measurement · score 0.20
- keratoconus 1 · score 0.11
- neoplasm · score 0.08
- colitis · score 0.08
- isolated agammaglobulinemia · score 0.06
- mean platelet volume · score 0.06
- body height · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHF5-F1 | alphafold | PREDICTED | 78.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHF5.
Amino-acid sequence (180 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IL17B?
The strongest Open Targets associations for IL17B are heel bone mineral density, bone quantitative ultrasound measurement, bilirubin measurement, diet measurement and keratoconus 1.
How long is the IL17B protein?
The Homo sapiens IL17B protein (UniProt Q9UHF5) is 180 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHF5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHF5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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