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Prenylcysteine oxidase 1 (PCYOX1)

Homo sapiens — UniProt Q9UHG3

Gene: PCYOX1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Prenylcysteine oxidase 1 (PCYOX1) is a protein from Homo sapiens identified by UniProt accession Q9UHG3, 505 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

  • UniProt accession: Q9UHG3; gene symbol PCYOX1.
  • Organism: Homo sapiens.
  • Length: 505 amino acids.
  • Top disease associations (Open Targets): blood protein measurement, chronotype measurement and alkaline phosphatase measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein namePrenylcysteine oxidase 1
UniProt accessionQ9UHG3
GenePCYOX1
OrganismHomo sapiens
Length505 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (44)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.43
  • chronotype measurement · score 0.42
  • alkaline phosphatase measurement · score 0.41
  • self reported educational attainment · score 0.37
  • mathematical ability · score 0.30
  • cognitive function measurement · score 0.30
  • balding measurement · score 0.23
  • sex hormone-binding globulin measurement · score 0.14
  • total cholesterol measurement · score 0.09
  • insulin like growth factor measurement · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UHG3-F1alphafoldPREDICTED91.30—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHG3.

Amino-acid sequence (505 residues)

MGRVVAELVS SLLGLWLLLC SCGCPEGAEL RAPPDKIAII GAGIGGTSAA YYLRQKFGKD VKIDLFEREE VGGRLATMMV QGQEYEAGGS VIHPLNLHMK RFVKDLGLSA VQASGGLLGI YNGETLVFEE SNWFIINVIK LVWRYGFQSL RMHMWVEDVL DKFMRIYRYQ SHDYAFSSVE KLLHALGGDD FLGMLNRTLL ETLQKAGFSE KFLNEMIAPV MRVNYGQSTD INAFVGAVSL SCSDSGLWAV EGGNKLVCSG LLQASKSNLI SGSVMYIEEK TKTKYTGNPT KMYEVVYQIG TETRSDFYDI VLVATPLNRK MSNITFLNFD PPIEEFHQYY QHIVTTLVKG ELNTSIFSSR PIDKFGLNTV LTTDNSDLFI NSIGIVPSVR EKEDPEPSTD GTYVWKIFSQ ETLTKAQILK LFLSYDYAVK KPWLAYPHYK PPEKCPSIIL HDRLYYLNGI ECAASAMEMS AIAAHNAALL AYHRWNGHTD MIDQDGLYEK LKTEL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCYOX1?

The strongest Open Targets associations for PCYOX1 are blood protein measurement, chronotype measurement, alkaline phosphatase measurement, self reported educational attainment and mathematical ability.

How long is the PCYOX1 protein?

The Homo sapiens PCYOX1 protein (UniProt Q9UHG3) is 505 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UHG3
GenePCYOX1
OrganismHomo sapiens
Length505
Binders0
Diseases44
View on UniProt