Probable ATP-dependent RNA helicase DDX20 (DDX20)
Homo sapiens — UniProt Q9UHI6
Data last refreshed: (UniProt release unknown)
Key facts
Probable ATP-dependent RNA helicase DDX20 (DDX20) is a protein from Homo sapiens identified by UniProt accession Q9UHI6, 824 residues long. MolForge cross-references it against 0 known binders and 161 disease associations.
- UniProt accession: Q9UHI6; gene symbol DDX20.
- Organism: Homo sapiens.
- Length: 824 amino acids.
- Top disease associations (Open Targets): body mass index, lean body mass and multisite chronic pain.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Probable ATP-dependent RNA helicase DDX20 |
|---|---|
| UniProt accession | Q9UHI6 |
| Gene | DDX20 |
| Organism | Homo sapiens |
| Length | 824 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (161)
Diseases linked to this target (Open Targets).
- body mass index · score 0.28
- lean body mass · score 0.24
- multisite chronic pain · score 0.24
- type 2 diabetes mellitus · score 0.23
- fat body mass · score 0.22
- self reported educational attainment · score 0.20
- waist circumference · score 0.19
- Opioid use measurement · score 0.19
- body fat percentage · score 0.15
- body weight · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHI6-F1 | alphafold | PREDICTED | 61.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHI6.
Amino-acid sequence (824 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DDX20?
The strongest Open Targets associations for DDX20 are body mass index, lean body mass, multisite chronic pain, type 2 diabetes mellitus and fat body mass.
How long is the DDX20 protein?
The Homo sapiens DDX20 protein (UniProt Q9UHI6) is 824 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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