Solute carrier family 23 member 1 (SLC23A1)
Homo sapiens — UniProt Q9UHI7
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 23 member 1 (SLC23A1) is a protein from Homo sapiens identified by UniProt accession Q9UHI7, 598 residues long. MolForge cross-references it against 1 known binders and 49 disease associations.
- UniProt accession: Q9UHI7; gene symbol SLC23A1.
- Organism: Homo sapiens.
- Length: 598 amino acids.
- Top disease associations (Open Targets): creatinine measurement, vitamin C measurement and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 23 member 1 |
|---|---|
| UniProt accession | Q9UHI7 |
| Gene | SLC23A1 |
| Organism | Homo sapiens |
| Length | 598 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.34
- vitamin C measurement · score 0.29
- glomerular filtration rate · score 0.18
- hypertrophic cardiomyopathy · score 0.15
- electrocardiography · score 0.11
- systolic blood pressure · score 0.06
- appendicular lean mass · score 0.05
- Crohn's disease · score 0.04
- cystinuria · score 0.04
- hyperdibasic aminoaciduria type 1 · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHI7-F1 | alphafold | PREDICTED | 81.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHI7.
Amino-acid sequence (598 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC23A1?
The strongest Open Targets associations for SLC23A1 are creatinine measurement, vitamin C measurement, glomerular filtration rate, hypertrophic cardiomyopathy and electrocardiography.
How long is the SLC23A1 protein?
The Homo sapiens SLC23A1 protein (UniProt Q9UHI7) is 598 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHI7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHI7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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