Scm-like with four MBT domains protein 1 (SFMBT1)
Homo sapiens — UniProt Q9UHJ3
Data last refreshed: (UniProt release unknown)
Key facts
Scm-like with four MBT domains protein 1 (SFMBT1) is a protein from Homo sapiens identified by UniProt accession Q9UHJ3, 866 residues long. MolForge cross-references it against 0 known binders and 97 disease associations.
- UniProt accession: Q9UHJ3; gene symbol SFMBT1.
- Organism: Homo sapiens.
- Length: 866 amino acids.
- Top disease associations (Open Targets): urate measurement, neurodegenerative disease and uric acid measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Scm-like with four MBT domains protein 1 |
|---|---|
| UniProt accession | Q9UHJ3 |
| Gene | SFMBT1 |
| Organism | Homo sapiens |
| Length | 866 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (97)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.33
- neurodegenerative disease · score 0.29
- uric acid measurement · score 0.27
- body height · score 0.23
- electrocardiography · score 0.22
- gout · score 0.20
- self reported educational attainment · score 0.20
- forced expiratory volume · score 0.18
- cognitive function measurement · score 0.17
- hemorrhoid · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHJ3-F1 | alphafold | PREDICTED | 74.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHJ3.
Amino-acid sequence (866 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SFMBT1?
The strongest Open Targets associations for SFMBT1 are urate measurement, neurodegenerative disease, uric acid measurement, body height and electrocardiography.
How long is the SFMBT1 protein?
The Homo sapiens SFMBT1 protein (UniProt Q9UHJ3) is 866 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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