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Protein FAM153A (FAM153A)

Homo sapiens — UniProt Q9UHL3

Gene: FAM153AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM153A (FAM153A) is a protein from Homo sapiens identified by UniProt accession Q9UHL3, 310 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

  • UniProt accession: Q9UHL3; gene symbol FAM153A.
  • Organism: Homo sapiens.
  • Length: 310 amino acids.
  • Top disease associations (Open Targets): body height, genetic disorder and mathematical ability.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM153A
UniProt accessionQ9UHL3
GeneFAM153A
OrganismHomo sapiens
Length310 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (7)

Diseases linked to this target (Open Targets).

  • body height · score 0.26
  • genetic disorder · score 0.12
  • mathematical ability · score 0.03
  • self reported educational attainment · score 0.02
  • eosinophil count · score 0.02
  • Obesity · score 0.00
  • cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UHL3-F1alphafoldPREDICTED51.69—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHL3.

Amino-acid sequence (310 residues)

MVDKDTERDI EMKRQLRRLR ELHLYSTWKK YQEAMKTSLG VPQCERDEGS LGKPLCPPEI LSETLPGSVK KRVCFPSEDH LEEFIAEHLP EASNQSLLTV AHADAGTQTN GDLEDLEEHG PGQTVSEEAT EVHTMEGDPD TLAEFLIRDV LQELSSYNGE EEDPEEVKTS LGVPQRGDLE DLEEHVPGQT VSEEATGVHM MQVDPATLAK SDLEDLEEHV PEQTVSEEAT GVHMMQVDPA TLAKQLEDST ITGSHQQMSA SPSSAPAEEA TEKTKVEEEV KTRKPKKKTR KPSKKSRWNV LKCWDIFNIF

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM153A?

The strongest Open Targets associations for FAM153A are body height, genetic disorder, mathematical ability, self reported educational attainment and eosinophil count.

How long is the FAM153A protein?

The Homo sapiens FAM153A protein (UniProt Q9UHL3) is 310 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UHL3
GeneFAM153A
OrganismHomo sapiens
Length310
Binders0
Diseases7
View on UniProt