Dipeptidyl peptidase 2 (DPP7)
Homo sapiens — UniProt Q9UHL4
Data last refreshed: (UniProt release unknown)
Key facts
Dipeptidyl peptidase 2 (DPP7) is a protein from Homo sapiens identified by UniProt accession Q9UHL4, 492 residues long. MolForge cross-references it against 1 known binders and 65 disease associations.
- UniProt accession: Q9UHL4; gene symbol DPP7.
- Organism: Homo sapiens.
- Length: 492 amino acids.
- Top disease associations (Open Targets): blood protein measurement, BMI-adjusted waist-hip ratio and cerebrospinal fluid biomarker measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dipeptidyl peptidase 2 |
|---|---|
| UniProt accession | Q9UHL4 |
| Gene | DPP7 |
| Organism | Homo sapiens |
| Length | 492 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.25
- BMI-adjusted waist-hip ratio · score 0.23
- cerebrospinal fluid biomarker measurement · score 0.18
- platelet count · score 0.16
- aspartate aminotransferase measurement · score 0.14
- high density lipoprotein cholesterol measurement · score 0.11
- body height · score 0.09
- monocyte count · score 0.09
- monocyte percentage of leukocytes · score 0.07
- hemoglobin measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHL4-F1 | alphafold | PREDICTED | 94.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHL4.
Amino-acid sequence (492 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DPP7?
The strongest Open Targets associations for DPP7 are blood protein measurement, BMI-adjusted waist-hip ratio, cerebrospinal fluid biomarker measurement, platelet count and aspartate aminotransferase measurement.
How long is the DPP7 protein?
The Homo sapiens DPP7 protein (UniProt Q9UHL4) is 492 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHL4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHL4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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