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Cell surface hyaluronidase CEMIP2 (CEMIP2)

Homo sapiens — UniProt Q9UHN6

Gene: CEMIP2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cell surface hyaluronidase CEMIP2 (CEMIP2) is a protein from Homo sapiens identified by UniProt accession Q9UHN6, 1383 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

  • UniProt accession: Q9UHN6; gene symbol CEMIP2.
  • Organism: Homo sapiens.
  • Length: 1383 amino acids.
  • Top disease associations (Open Targets): Hypertelorism, Retinal dystrophy and Inguinal hernia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCell surface hyaluronidase CEMIP2
UniProt accessionQ9UHN6
GeneCEMIP2
OrganismHomo sapiens
Length1383 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (68)

Diseases linked to this target (Open Targets).

  • Hypertelorism · score 0.43
  • Retinal dystrophy · score 0.43
  • Inguinal hernia · score 0.43
  • myopia · score 0.43
  • Myopia · score 0.43
  • spondyloepimetaphyseal dysplasia with joint laxity · score 0.43
  • Abnormal sternum morphology · score 0.43
  • total blood protein measurement · score 0.36
  • FEV/FVC ratio · score 0.36
  • attention deficit hyperactivity disorder · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UHN6-F1alphafoldPREDICTED89.56—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHN6.

Amino-acid sequence (1383 residues)

MYATDSRGHS PAFLQPQNGN SRHPSGYVPG KVVPLRPPPP PKSQASAKFT SIRREDRATF AFSPEEQQAQ RESQKQKRHK NTFICFAITS FSFFIALAII LGISSKYAPD ENCPDQNPRL RNWDPGQDSA KQVVIKEGDM LRLTSDATVH SIVIQDGGLL VFGDNKDGSR NITLRTHYIL IQDGGALHIG AEKCRYKSKA TITLYGKSDE GESMPTFGKK FIGVEAGGTL ELHGARKASW TLLARTLNSS GLPFGSYTFE KDFSRGLNVR VIDQDTAKIL ESERFDTHEY RNESRRLQEF LRFQDPGRIV AIAVGDSAAK SLLQGTIQMI QERLGSELIQ GLGYRQAWAL VGVIDGGSTS CNESVRNYEN HSSGGKALAQ REFYTVDGQK FSVTAYSEWI EGVSLSGFRV EVVDGVKLNL LDDVSSWKPG DQIVVASTDY SMYQAEEFTL LPCSECSHFQ VKVKETPQFL HMGEIIDGVD MRAEVGILTR NIVIQGEVED SCYAENQCQF FDYDTFGGHI MIMKNFTSVH LSYVELKHMG QQQMGRYPVH FHLCGDVDYK GGYRHATFVD GLSIHHSFSR CITVHGTNGL LIKDTIGFDT LGHCFFLEDG IEQRNTLFHN LGLLTKPGTL LPTDRNNSMC TTMRDKVFGN YIPVPATDCM AVSTFWIAHP NNNLINNAAA GSQDAGIWYL FHKEPTGESS GLQLLAKPEL TPLGIFYNNR VHSNFKAGLF IDKGVKTTNS SAADPREYLC LDNSARFRPH QDANPEKPRV AALIDRLIAF KNNDNGAWVR GGDIIVQNSA FADNGIGLTF ASDGSFPSDE GSSQEVSESL FVGESRNYGF QGGQNKYVGT GGIDQKPRTL PRNRTFPIRG FQIYDGPIHL TRSTFKKYVP TPDRYSSAIG FLMKNSWQIT PRNNISLVKF GPHVSLNVFF GKPGPWFEDC EMDGDKNSIF HDIDGSVTGY KDAYVGRMDN YLIRHPSCVN VSKWNAVICS GTYAQVYVQT WSTQNLSMTI TRDEYPSNPM VLRGINQKAA FPQYQPVVML EKGYTIHWNG PAPRTTFLYL VNFNKNDWIR VGLCYPSNTS FQVTFGYLQR QNGSLSKIEE YEPVHSLEEL QRKQSERKFY FDSSTGLLFL YLKAKSHRHG HSYCSSQGCE RVKIQAATDS KDISNCMAKA YPQYYRKPSV VKRMPAMLTG LCQGCGTRQV VFTSDPHKSY LPVQFQSPDK AETQRGDPSV ISVNGTDFTF RSAGVLLLVV DPCSVPFRLT EKTVFPLADV SRIEEYLKTG IPPRSIVLLS TRGEIKQLNI SHLLVPLGLA KPAHLYDKGS TIFLGFSGNF KPSWTKLFTS PAGQGLGVLE QFIPLQLDEY GCPRATTVRR RDLELLKQAS KAH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CEMIP2?

The strongest Open Targets associations for CEMIP2 are Hypertelorism, Retinal dystrophy, Inguinal hernia, myopia and Myopia.

How long is the CEMIP2 protein?

The Homo sapiens CEMIP2 protein (UniProt Q9UHN6) is 1383 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UHN6
GeneCEMIP2
OrganismHomo sapiens
Length1383
Binders0
Diseases68
View on UniProt