Small muscular protein (SMPX)
Homo sapiens — UniProt Q9UHP9
Data last refreshed: (UniProt release unknown)
Key facts
Small muscular protein (SMPX) is a protein from Homo sapiens identified by UniProt accession Q9UHP9, 88 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q9UHP9; gene symbol SMPX.
- Organism: Homo sapiens.
- Length: 88 amino acids.
- Top disease associations (Open Targets): myopathy, distal, 7, adult-onset, X-linked, X-linked nonsyndromic hearing loss and nonsyndromic genetic hearing loss.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small muscular protein |
|---|---|
| UniProt accession | Q9UHP9 |
| Gene | SMPX |
| Organism | Homo sapiens |
| Length | 88 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- myopathy, distal, 7, adult-onset, X-linked · score 0.63
- X-linked nonsyndromic hearing loss · score 0.60
- nonsyndromic genetic hearing loss · score 0.37
- hearing loss · score 0.37
- X-linked deafness · score 0.33
- Hearing impairment · score 0.30
- genetic disorder · score 0.12
- deafness · score 0.10
- autosomal recessive nonsyndromic hearing loss 1B · score 0.08
- Non-syndromic genetic deafness · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHP9-F1 | alphafold | PREDICTED | 67.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHP9.
Amino-acid sequence (88 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMPX?
The strongest Open Targets associations for SMPX are myopathy, distal, 7, adult-onset, X-linked, X-linked nonsyndromic hearing loss, nonsyndromic genetic hearing loss, hearing loss and X-linked deafness.
How long is the SMPX protein?
The Homo sapiens SMPX protein (UniProt Q9UHP9) is 88 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHP9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHP9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.