Transcription elongation factor A protein-like 9 (TCEAL9)
Homo sapiens — UniProt Q9UHQ7
Data last refreshed: (UniProt release unknown)
Key facts
Transcription elongation factor A protein-like 9 (TCEAL9) is a protein from Homo sapiens identified by UniProt accession Q9UHQ7, 104 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q9UHQ7; gene symbol TCEAL9.
- Organism: Homo sapiens.
- Length: 104 amino acids.
- Top disease associations (Open Targets): Blackfan-Diamond anemia, alpha thalassemia-intellectual disability syndrome type 1 and Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transcription elongation factor A protein-like 9 |
|---|---|
| UniProt accession | Q9UHQ7 |
| Gene | TCEAL9 |
| Organism | Homo sapiens |
| Length | 104 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- Blackfan-Diamond anemia · score 0.08
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.06
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.06
- small cell lung carcinoma · score 0.06
- thrombocytopenia 4 · score 0.06
- macrothrombocytopenia, isolated, 2, autosomal dominant · score 0.06
- beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.05
- hemolytic anemia due to adenylate kinase deficiency · score 0.05
- Constitutional sideroblastic anemia · score 0.05
- Heinz body anemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHQ7-F1 | alphafold | PREDICTED | 67.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHQ7.
Amino-acid sequence (104 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TCEAL9?
The strongest Open Targets associations for TCEAL9 are Blackfan-Diamond anemia, alpha thalassemia-intellectual disability syndrome type 1, Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16, small cell lung carcinoma and thrombocytopenia 4.
How long is the TCEAL9 protein?
The Homo sapiens TCEAL9 protein (UniProt Q9UHQ7) is 104 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHQ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHQ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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