BAR/IMD domain-containing adapter protein 2-like 1 (BAIAP2L1)
Homo sapiens — UniProt Q9UHR4
Data last refreshed: (UniProt release unknown)
Key facts
BAR/IMD domain-containing adapter protein 2-like 1 (BAIAP2L1) is a protein from Homo sapiens identified by UniProt accession Q9UHR4, 511 residues long. MolForge cross-references it against 0 known binders and 135 disease associations.
- UniProt accession: Q9UHR4; gene symbol BAIAP2L1.
- Organism: Homo sapiens.
- Length: 511 amino acids.
- Top disease associations (Open Targets): testosterone measurement, neutrophil count and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BAR/IMD domain-containing adapter protein 2-like 1 |
|---|---|
| UniProt accession | Q9UHR4 |
| Gene | BAIAP2L1 |
| Organism | Homo sapiens |
| Length | 511 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (135)
Diseases linked to this target (Open Targets).
- testosterone measurement · score 0.46
- neutrophil count · score 0.45
- sex hormone-binding globulin measurement · score 0.45
- low density lipoprotein cholesterol measurement · score 0.42
- alkaline phosphatase measurement · score 0.40
- leukocyte count · score 0.39
- apolipoprotein B measurement · score 0.38
- breast carcinoma · score 0.37
- lymphocyte count · score 0.35
- monocyte count · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHR4-F1 | alphafold | PREDICTED | 72.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHR4.
Amino-acid sequence (511 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BAIAP2L1?
The strongest Open Targets associations for BAIAP2L1 are testosterone measurement, neutrophil count, sex hormone-binding globulin measurement, low density lipoprotein cholesterol measurement and alkaline phosphatase measurement.
How long is the BAIAP2L1 protein?
The Homo sapiens BAIAP2L1 protein (UniProt Q9UHR4) is 511 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHR4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHR4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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