SAP30-binding protein (SAP30BP)
Homo sapiens — UniProt Q9UHR5
Data last refreshed: (UniProt release unknown)
Key facts
SAP30-binding protein (SAP30BP) is a protein from Homo sapiens identified by UniProt accession Q9UHR5, 308 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.
- UniProt accession: Q9UHR5; gene symbol SAP30BP.
- Organism: Homo sapiens.
- Length: 308 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, rotator cuff tear and Blackfan-Diamond anemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SAP30-binding protein |
|---|---|
| UniProt accession | Q9UHR5 |
| Gene | SAP30BP |
| Organism | Homo sapiens |
| Length | 308 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (77)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- rotator cuff tear · score 0.14
- Blackfan-Diamond anemia · score 0.11
- Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 · score 0.07
- alpha thalassemia-intellectual disability syndrome type 1 · score 0.07
- hemolytic anemia due to adenylate kinase deficiency · score 0.06
- Heinz body anemia · score 0.06
- delta-beta-thalassemia · score 0.06
- Constitutional sideroblastic anemia · score 0.06
- X-linked sideroblastic anemia 1 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHR5-F1 | alphafold | PREDICTED | 64.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHR5.
Amino-acid sequence (308 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SAP30BP?
The strongest Open Targets associations for SAP30BP are neurodegenerative disease, rotator cuff tear, Blackfan-Diamond anemia, Alpha-thalassemia - intellectual disability syndrome linked to chromosome 16 and alpha thalassemia-intellectual disability syndrome type 1.
How long is the SAP30BP protein?
The Homo sapiens SAP30BP protein (UniProt Q9UHR5) is 308 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHR5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHR5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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