SERTA domain-containing protein 1 (SERTAD1)
Homo sapiens — UniProt Q9UHV2
Data last refreshed: (UniProt release unknown)
Key facts
SERTA domain-containing protein 1 (SERTAD1) is a protein from Homo sapiens identified by UniProt accession Q9UHV2, 236 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q9UHV2; gene symbol SERTAD1.
- Organism: Homo sapiens.
- Length: 236 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, monocyte percentage of leukocytes and myeloid white cell count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SERTA domain-containing protein 1 |
|---|---|
| UniProt accession | Q9UHV2 |
| Gene | SERTAD1 |
| Organism | Homo sapiens |
| Length | 236 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- monocyte percentage of leukocytes · score 0.25
- myeloid white cell count · score 0.23
- granulocyte percentage of myeloid white cells · score 0.12
- neutrophil count · score 0.11
- cancer · score 0.09
- Recurrent tonsillitis · score 0.08
- leukocyte count · score 0.08
- mean corpuscular volume · score 0.06
- chronic pancreatitis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHV2-F1 | alphafold | PREDICTED | 62.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHV2.
Amino-acid sequence (236 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SERTAD1?
The strongest Open Targets associations for SERTAD1 are neurodegenerative disease, monocyte percentage of leukocytes, myeloid white cell count, granulocyte percentage of myeloid white cells and neutrophil count.
How long is the SERTAD1 protein?
The Homo sapiens SERTAD1 protein (UniProt Q9UHV2) is 236 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHV2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHV2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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