Enolase-phosphatase E1 (ENOPH1)
Homo sapiens — UniProt Q9UHY7
Data last refreshed: (UniProt release unknown)
Key facts
Enolase-phosphatase E1 (ENOPH1) is a protein from Homo sapiens identified by UniProt accession Q9UHY7, 261 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9UHY7; gene symbol ENOPH1.
- Organism: Homo sapiens.
- Length: 261 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroinflammatory disorder and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Enolase-phosphatase E1 |
|---|---|
| UniProt accession | Q9UHY7 |
| Gene | ENOPH1 |
| Organism | Homo sapiens |
| Length | 261 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- neuroinflammatory disorder · score 0.37
- lysosomal storage disease · score 0.15
- hepatocellular carcinoma · score 0.08
- adolescent idiopathic scoliosis · score 0.05
- breast cancer · score 0.03
- neoplasm · score 0.03
- BMI-adjusted waist circumference · score 0.02
- lymphocyte count · score 0.02
- Cerebral ischemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UHY7-F1 | alphafold | PREDICTED | 95.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UHY7.
Amino-acid sequence (261 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENOPH1?
The strongest Open Targets associations for ENOPH1 are neurodegenerative disease, neuroinflammatory disorder, lysosomal storage disease, hepatocellular carcinoma and adolescent idiopathic scoliosis.
How long is the ENOPH1 protein?
The Homo sapiens ENOPH1 protein (UniProt Q9UHY7) is 261 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UHY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UHY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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