Solute carrier organic anion transporter family…

About Solute carrier organic anion transporter family member 3A1

Solute carrier organic anion transporter family member 3A1 (SLCO3A1) is a protein from Homo sapiens identified by UniProt accession Q9UIG8, 710 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

Target properties

Protein name	Solute carrier organic anion transporter family member 3A1
UniProt accession	Q9UIG8
Gene	SLCO3A1
Organism	Homo sapiens
Length	710 residues
Molecular weight	—
EC numbers	—
Target class	Transporter (inferred from UniProt keywords / EC)
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (62)

Diseases linked to this target (Open Targets).

body mass index · score 0.50
body fat percentage · score 0.48
lean body mass · score 0.44
fat body mass · score 0.44
alcohol dependence · score 0.34
alcohol abuse · score 0.34
PHF-tau measurement · score 0.33
waist circumference · score 0.32
body height · score 0.32
waist-hip ratio · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9UIG8-F1	alphafold	PREDICTED	75.51	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UIG8.

Amino-acid sequence (710 residues)

MQGKKPGGSS GGGRSGELQG DEAQRNKKKK KKVSCFSNIK IFLVSECALM LAQGTVGAYL VSVLTTLERR FNLQSADVGV IASSFEIGNL ALILFVSYFG ARGHRPRLIG CGGIVMALGA LLSALPEFLT HQYKYEAGEI RWGAEGRDVC AANGSGGDEG PDPDLICRNR TATNMMYLLL IGAQVLLGIG ATPVQPLGVS YIDDHVRRKD SSLYIGILFT MLVFGPACGF ILGSFCTKIY VDAVFIDTSN LDITPDDPRW IGAWWGGFLL CGALLFFSSL LMFGFPQSLP PHSEPAMESE QAMLSEREYE RPKPSNGVLR HPLEPDSSAS CFQQLRVIPK VTKHLLSNPV FTCIILAACM EIAVVAGFAA FLGKYLEQQF NLTTSSANQL LGMTAIPCAC LGIFLGGLLV KKLSLSALGA IRMAMLVNLV STACYVSFLF LGCDTGPVAG VTVPYGNSTA PGSALDPYSP CNNNCECQTD SFTPVCGADG ITYLSACFAG CNSTNLTGCA CLTTVPAENA TVVPGKCPSP GCQEAFLTFL CVMCICSLIG AMAQTPSVII LIRTVSPELK SYALGVLFLL LRLLGFIPPP LIFGAGIDST CLFWSTFCGE QGACVLYDNV VYRYLYVSIA IALKSFAFIL YTTTWQCLRK NYKRYIKNHE GGLSTSEFFA STLTLDNLGR DPVPANQTHR TKFIYNLEDH EWCENMESVL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Solute carrier organic anion transporter family member 3A1 (SLCO3A1)