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Solute carrier organic anion transporter family member 3A1 (SLCO3A1)

Homo sapiens — UniProt Q9UIG8

Gene: SLCO3A1Homo sapiensSwissProt reviewedTransporter

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier organic anion transporter family member 3A1 (SLCO3A1) is a protein from Homo sapiens identified by UniProt accession Q9UIG8, 710 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.

  • UniProt accession: Q9UIG8; gene symbol SLCO3A1.
  • Organism: Homo sapiens.
  • Length: 710 amino acids.
  • Target class: Transporter.
  • Top disease associations (Open Targets): body mass index, body fat percentage and lean body mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier organic anion transporter family member 3A1
UniProt accessionQ9UIG8
GeneSLCO3A1
OrganismHomo sapiens
Length710 residues
Molecular weight—
EC numbers—
Target classTransporter (inferred from UniProt keywords / EC)
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (62)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.50
  • body fat percentage · score 0.48
  • lean body mass · score 0.44
  • fat body mass · score 0.44
  • alcohol dependence · score 0.34
  • alcohol abuse · score 0.34
  • PHF-tau measurement · score 0.33
  • waist circumference · score 0.32
  • body height · score 0.32
  • waist-hip ratio · score 0.32

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9UIG8-F1alphafoldPREDICTED75.51—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UIG8.

Amino-acid sequence (710 residues)

MQGKKPGGSS GGGRSGELQG DEAQRNKKKK KKVSCFSNIK IFLVSECALM LAQGTVGAYL VSVLTTLERR FNLQSADVGV IASSFEIGNL ALILFVSYFG ARGHRPRLIG CGGIVMALGA LLSALPEFLT HQYKYEAGEI RWGAEGRDVC AANGSGGDEG PDPDLICRNR TATNMMYLLL IGAQVLLGIG ATPVQPLGVS YIDDHVRRKD SSLYIGILFT MLVFGPACGF ILGSFCTKIY VDAVFIDTSN LDITPDDPRW IGAWWGGFLL CGALLFFSSL LMFGFPQSLP PHSEPAMESE QAMLSEREYE RPKPSNGVLR HPLEPDSSAS CFQQLRVIPK VTKHLLSNPV FTCIILAACM EIAVVAGFAA FLGKYLEQQF NLTTSSANQL LGMTAIPCAC LGIFLGGLLV KKLSLSALGA IRMAMLVNLV STACYVSFLF LGCDTGPVAG VTVPYGNSTA PGSALDPYSP CNNNCECQTD SFTPVCGADG ITYLSACFAG CNSTNLTGCA CLTTVPAENA TVVPGKCPSP GCQEAFLTFL CVMCICSLIG AMAQTPSVII LIRTVSPELK SYALGVLFLL LRLLGFIPPP LIFGAGIDST CLFWSTFCGE QGACVLYDNV VYRYLYVSIA IALKSFAFIL YTTTWQCLRK NYKRYIKNHE GGLSTSEFFA STLTLDNLGR DPVPANQTHR TKFIYNLEDH EWCENMESVL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLCO3A1?

The strongest Open Targets associations for SLCO3A1 are body mass index, body fat percentage, lean body mass, fat body mass and alcohol dependence.

How long is the SLCO3A1 protein?

The Homo sapiens SLCO3A1 protein (UniProt Q9UIG8) is 710 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9UIG8
GeneSLCO3A1
OrganismHomo sapiens
Length710
Binders0
Diseases62
View on UniProt