Testis-specific Y-encoded-like protein 4 (TSPYL4)
Homo sapiens — UniProt Q9UJ04
Data last refreshed: (UniProt release unknown)
Key facts
Testis-specific Y-encoded-like protein 4 (TSPYL4) is a protein from Homo sapiens identified by UniProt accession Q9UJ04, 414 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9UJ04; gene symbol TSPYL4.
- Organism: Homo sapiens.
- Length: 414 amino acids.
- Top disease associations (Open Targets): FEV/FVC ratio, total cholesterol measurement and C-reactive protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Testis-specific Y-encoded-like protein 4 |
|---|---|
| UniProt accession | Q9UJ04 |
| Gene | TSPYL4 |
| Organism | Homo sapiens |
| Length | 414 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.23
- total cholesterol measurement · score 0.19
- C-reactive protein measurement · score 0.09
- alcohol dependence measurement · score 0.08
- electroencephalogram measurement · score 0.08
- refractive error measurement · score 0.06
- attention deficit hyperactivity disorder · score 0.06
- hemoglobin measurement · score 0.04
- systemic lupus erythematosus · score 0.04
- body height · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9UJ04-F1 | alphafold | PREDICTED | 63.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9UJ04.
Amino-acid sequence (414 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSPYL4?
The strongest Open Targets associations for TSPYL4 are FEV/FVC ratio, total cholesterol measurement, C-reactive protein measurement, alcohol dependence measurement and electroencephalogram measurement.
How long is the TSPYL4 protein?
The Homo sapiens TSPYL4 protein (UniProt Q9UJ04) is 414 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9UJ04 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9UJ04 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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